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Last updated: 2016/10/16
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CASP4 polyclonal antibody

  • Catalog # : PAB9824
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CASP4.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human CASP4.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 2.
  • Interleukin-18.
    Gracie JA, Robertson SE, McInnes IB.J Leukoc Biol. 2003 Feb;73(2):213-24.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of CASP4 in Ramos cells with CASP4 polyclonal antibody at (A) 0.5 and (B) 1 ug/mL .
  • Immunohistochemistry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 837
  • Gene Name:
  • CASP4
  • Gene Alias:
  • Gene Description:
  • caspase 4, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • apoptotic cysteine protease Mih1/TX,caspase 4,caspase 4, apoptosis-related cysteine protease
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