TLR9 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TLR9.
Immunogen
A synthetic peptide corresponding to internal region of human TLR9.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TLR9 expression in Jurkat cell lysate with TLR9 polyclonal antibody (Cat # PAB9737) at 0.5 ug/mL .Immunohistochemistry
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Gene Info — TLR9
Entrez GeneID
54106Gene Name
TLR9
Gene Alias
CD289
Gene Description
toll-like receptor 9
Omim ID
605474Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
- Adenocarcinoma
- Anemia
- Arthritis
- Arthropathy
- Aspergillosis
- Asthma
- Atherosclerosis
- Behcet Syndrome
- Birth Weight
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Publication Reference
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The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction.
McGettrick AF, O'Neill LA.
Molecular Immunology 2004 Jul; 41(6-7):577.
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Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors.
Nishiya T, DeFranco AL.
The Journal of Biological Chemistry 2004 Feb; 279(18):19008.
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The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction.
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