Gabra6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against a recombinant Gabra6.
Immunogen
Recombinant protein corresponding to rat Gabra6.
Host
Rabbit
Theoretical MW (kDa)
57
Reactivity
Mouse, Rat
Form
Liquid
Purification
Affinity purification
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
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Gene Info — Gabra6
Entrez GeneID
29708Protein Accession#
P30191Gene Name
Gabra6
Gene Alias
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Gene Description
gamma-aminobutyric acid (GABA) A receptor, alpha 6
Gene Ontology
HyperlinkGene Summary
O
Other Designations
GABA-A receptor alpha-6 subunit|gamma-aminobutyric acid A receptor, alpha 6|gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6|gamma-aminobutyric acid A receptor, alpha 6
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Publication Reference
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Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.
Ogris W, Poltl A, Hauer B, Ernst M, Oberto A, Wulff P, Hoger H, Wisden W, Sieghart W.
Biochemical Pharmacology 2004 Oct; 68(8):1621.
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Subunit composition and quantitative importance of GABA(A) receptor subtypes in the cerebellum of mouse and rat.
Poltl A, Hauer B, Fuchs K, Tretter V, Sieghart W.
Journal of Neurochemistry 2003 Dec; 87(6):1444.
Application：IP, WB, Human, Mouse, Rat, HEK 293 cells, Mouse and Rat cerebellar extracts.
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Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.
McKernan RM, Rosahl TW, Reynolds DS, Sur C, Wafford KA, Atack JR, Farrar S, Myers J, Cook G, Ferris P, Garrett L, Bristow L, Marshall G, Macaulay A, Brown N, Howell O, Moore KW, Carling RW, Street LJ, Castro JL, Ragan CI, Dawson GR, Whiting PJ.
Nature Neuroscience 2000 Jun; 3(6):587.
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Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.
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