Gabrd polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant Gabrd.
Immunogen
Recombinant protein corresponding to N-terminus rat Gabrd.
Host
Rabbit
Theoretical MW (kDa)
52
Reactivity
Mouse, Rat
Form
Liquid
Purification
Affinity purification
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot (tissue lysate) analysis of (1) mouse whole brain, (2) mouse synaptic plasma membrane lysates showing specific immunolabeling of the δ-subunit of the GABAA-R. -
Gene Info — Gabrd
Entrez GeneID
29689Protein Accession#
P18506Gene Name
Gabrd
Gene Alias
GABAA-RD, MGC105467
Gene Description
gamma-aminobutyric acid (GABA) A receptor, delta
Gene Ontology
HyperlinkGene Summary
O
Other Designations
GABA-A receptor delta-subunit|GABAA receptor delta subunit|gamma-aminobutyric acid A receptor, delta|gamma-aminobutyric acid (GABA-A) receptor, subunit delta|gamma-aminobutyric acid A receptor, delta
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Publication Reference
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Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.
Ogris W, Poltl A, Hauer B, Ernst M, Oberto A, Wulff P, Hoger H, Wisden W, Sieghart W.
Biochemical Pharmacology 2004 Oct; 68(8):1621.
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Subunit composition and quantitative importance of GABA(A) receptor subtypes in the cerebellum of mouse and rat.
Poltl A, Hauer B, Fuchs K, Tretter V, Sieghart W.
Journal of Neurochemistry 2003 Dec; 87(6):1444.
Application:IP, WB, Human, Mouse, Rat, HEK 293 cells, Mouse and Rat cerebellar extracts.
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Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans.
Wallner M, Hanchar HJ, Olsen RW.
PNAS 2003 Dec; 100(25):15218.
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Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.
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