Gabra3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
Western blot of mouse brain lysates from wild type (Control, lane 1) and Gabra3 knockout (alpha K/O, lane 2) animals showing specific immunolabeling of the ~51k Gabra3 subunit of the GABAA-R. The labeling was absent from a lysate prepared from Gabra3 knockout animals.
-
Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant Gabra3.
Immunogen
Recombinant protein corresponding to N-terminus rat Gabra3.
Host
Rabbit
Theoretical MW (kDa)
51
Reactivity
Mouse, Rat
Form
Liquid
Purification
Affinity purification
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot of mouse brain lysates from wild type (Control, lane 1) and Gabra3 knockout (alpha K/O, lane 2) animals showing specific immunolabeling of the ~51k Gabra3 subunit of the GABAA-R. The labeling was absent from a lysate prepared from Gabra3 knockout animals. -
Gene Info — Gabra3
Entrez GeneID
24947Protein Accession#
P20236Gene Name
Gabra3
Gene Alias
-
Gene Description
gamma-aminobutyric acid (GABA) A receptor, alpha 3
Gene Ontology
HyperlinkGene Summary
O
Other Designations
GABA-A receptor alpha-3 subunit|Gamma-animobutyric acid (GABA) A receptor alpha 3|Gamma-animobutyric acid (GABA) A receptor, alpha 3|gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3|gamma-aminobutyric acid receptor, subunit alpha 3
-
Publication Reference
-
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.
Ogris W, Poltl A, Hauer B, Ernst M, Oberto A, Wulff P, Hoger H, Wisden W, Sieghart W.
Biochemical Pharmacology 2004 Oct; 68(8):1621.
-
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.
McKernan RM, Rosahl TW, Reynolds DS, Sur C, Wafford KA, Atack JR, Farrar S, Myers J, Cook G, Ferris P, Garrett L, Bristow L, Marshall G, Macaulay A, Brown N, Howell O, Moore KW, Carling RW, Street LJ, Castro JL, Ragan CI, Dawson GR, Whiting PJ.
Nature Neuroscience 2000 Jun; 3(6):587.
-
Prevalence of the GABAA receptor assemblies containing alpha1-subunit in the rat cerebellum and cerebral cortex as determined by immunoprecipitation: lack of modulation by chronic ethanol administration.
Mehta AK, Ticku MK.
Brain Research. Molecular Brain Research 1999 Apr; 67(1):194.
Application：IHC, WB-Ti, Rat, Rat cerebral cortex.
-
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com