App polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~115 KDa APP protein. Using App polyclonal antibody (Cat # PAB9629).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of App.
Immunogen
A synthetic peptide corresponding to C-terminus rat App.
Host
Rabbit
Theoretical MW (kDa)
115
Reactivity
Chicken, Dog, Human, Mouse, Primates, Rat
Form
Liquid
Purification
Affinity purification
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~115 KDa APP protein. Using App polyclonal antibody (Cat # PAB9629). -
Gene Info — App
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Publication Reference
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Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/Cdk5 and p25/Cdk5.
Liu F, Su Y, Li B, Zhou Y, Ryder J, Gonzalez-DeWhitt P, May PC, Ni B.
FEBS Letters 2003 Jul; 547(1-3):193.
Application：WB-Tr, Human, HEK 293, SH-SY5Y cells.
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APP processing and synaptic function.
Kamenetz F, Tomita T, Hsieh H, Seabrook G, Borchelt D, Iwatsubo T, Sisodia S, Malinow R.
Neuron 2003 Mar; 37(6):925.
Application：WB-Ti, Rat, Hippocampal.
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Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid.
Ando K, Iijima KI, Elliott JI, Kirino Y, Suzuki T.
The Journal of Biological Chemistry 2001 Oct; 276(43):40353.
Application：IP, WB-Ti, Rat, Rat brains.
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Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/Cdk5 and p25/Cdk5.
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