Snap25 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Snap25.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus rat Snap25.
Host
Rabbit
Theoretical MW (kDa)
25
Reactivity
Bovine, Chicken, Dog, Guinea pig, Human, Mouse, Primates, Rat, Zebra fish
Form
Liquid
Purification
Affinity purification
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot of rat cortex lysate showing specific labeling of the ~25k Snap25 protein. Using Snap25 polyclonal antibody (Cat # PAB9622). -
Gene Info — Snap25
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Publication Reference
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Negative regulation of neurotransmitter release by calpain: a possible involvement of specific SNAP-25 cleavage.
Ando K, Kudo Y, Takahashi M.
Journal of Neurochemistry 2005 Aug; 94(3):651.
Application:WB-Ce, Rat, Cerebellar granule cells.
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Altered levels of the synaptosomal associated protein SNAP-25 in hippocampus of subjects with mood disorders and schizophrenia.
Fatemi SH, Earle JA, Stary JM, Lee S, Sedgewick J.
Neuroreport 2001 Oct; 12(15):3257.
Application:IHC-Fr, Human, Human ventral hippocampus.
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Decreased levels of synaptosomal associated protein 25 in the brain of patients with Down syndrome and Alzheimer's disease.
Greber S, Lubec G, Cairns N, Fountoulakis M.
Electrophoresis 1999 Apr; 20(4-5):928.
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Negative regulation of neurotransmitter release by calpain: a possible involvement of specific SNAP-25 cleavage.
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