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Last updated: 2016/11/27
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DDC polyclonal antibody

  • Catalog # : PAB9598
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of DDC.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus human DDC.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 55
  • Reactivity:
  • Bovine, Dog, Guinea pig, Human, Rabbit, Rat, Sheep
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot of 5 ug of bovine adrenal medulla lysate showing specific immunolabeling of the ~55k DDC protein. Using DDC polyclonal antibody (Cat # PAB9598).
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1644
  • Gene Name:
  • DDC
  • Gene Alias:
  • AADC
  • Gene Description:
  • dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Gene Summary:
  • The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • L-Dopa decarboxylase,aromatic L-amino acid decarboxylase
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