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Last updated: 2017/6/25
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WNT4 polyclonal antibody

  • Catalog # : PAB9584
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of WNT4.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 10 of human WNT4.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 39
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody recognizes 39 KDa Wnt-4.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of WNT4 expression in Jurkat cell lysate.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • WNT4
  • Gene Alias:
  • SERKAL,WNT-4
  • Gene Description:
  • wingless-type MMTV integration site family, member 4
  • Gene Summary:
  • The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000002937,OTTHUMP00000044725,WNT-4 protein
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