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Last updated: 2016/12/11
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HDAC4 polyclonal antibody

  • Catalog # : PAB9522
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of HDAC4.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 10 of human HDAC4.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 140
  • Reactivity:
  • Chicken, Human, Mouse, Rat
  • Specificity:
  • This antibody detects ~140 KDa human HDAC-4.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of HDAC4 in mouse brain tissue lysate. An 140 kDa band can be detected.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9759
  • Gene Name:
  • HDAC4
  • Gene Alias:
  • HA6116,HD4,HDAC-A,HDACA,KIAA0288
  • Gene Description:
  • histone deacetylase 4
  • Gene Summary:
  • Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq
  • Other Designations:
  • histone deacetylase A
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