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Last updated: 2017/7/16
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HADHA/HADHB polyclonal antibody

  • Catalog # : PAB9092
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of HADHA/HADHB.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 750 of human HADHA/HADHB.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 84
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody recognizes 84 KDa TFP1.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of HADHA/HADHB expression with lysate from Jurkat cells (Lane 1,2) , NIH/3T3 cells (Lane 3) and rat kidney (Lane 4) .
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3030
  • Gene Name:
  • HADHA
  • Gene Alias:
  • ECHA,GBP,HADH,LCHAD,MGC1728,MTPA,TP-ALPHA
  • Gene Description:
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
  • Gene Summary:
  • This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq
  • Other Designations:
  • 3-ketoacyl-Coenzyme A (CoA) thiolase, alpha subunit,3-oxoacyl-CoA thiolase,78 kDa gastrin-binding protein,OTTHUMP00000122457,mitochondrial long-chain 2-enoyl-Coenzyme A (CoA) hydratase, alpha subunit,mitochondrial long-chain L-3-hydroxyacyl-Coenzyme A (Co
  • Gene Information
  • Entrez GeneID:
  • 3032
  • Gene Name:
  • HADHB
  • Gene Alias:
  • ECHB,MGC87480,MSTP029,TP-BETA
  • Gene Description:
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
  • Gene Summary:
  • This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found; however, their full-length nature is not known. [provided by RefSeq
  • Other Designations:
  • 2-enoyl-Coenzyme A (CoA) hydratase, beta subunit,3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit,acetyl-CoA acyltransferase,beta-ketothiolase,hydroxyacyl-Coenzyme A (CoA) dehydrogenase, beta subunit,mitochondrial
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