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Last updated: 2016/10/16
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PSMC5 polyclonal antibody

  • Catalog # : PAB9089
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PSMC5.
  • Immunogen:
  • A synthetic peptide corresponding to human PSMC5.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody recognizes the TRIP1(SUG1).
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1:500-1:2500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.02% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 5705
  • Gene Name:
  • PSMC5
  • Gene Alias:
  • S8,SUG1,TBP10,TRIP1,p45,p45/SUG
  • Gene Description:
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5
  • Gene Summary:
  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. [provided by RefSeq
  • Other Designations:
  • MSUG1 protein,Tat-binding protein homolog 10,proteasome 26S ATPase subunit 5,proteasome subunit p45,thyroid receptor interactor 1
  • Gene Pathway
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