MYOC polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MYOC.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human MYOC.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:500)
Immunoprecipitation (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of MYOC polyclonal antibody (Cat # PAB8971) with Myocillin positive control at 1:400 dilution.Immunohistochemistry
Immunoprecipitation
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Gene Info — MYOC
Entrez GeneID
4653Gene Name
MYOC
Gene Alias
GLC1A, GPOA, JOAG, JOAG1, TIGR, myocilin
Gene Description
myocilin, trabecular meshwork inducible glucocorticoid response
Gene Ontology
HyperlinkGene Summary
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq
Other Designations
OTTHUMP00000032681|mutated trabecular meshwork-induced glucocorticoid response protein|myocilin
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