JMJD2C polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of JMJD2C.
Immunogen
A synthetic peptide corresponding to N-terminus amino acids 502-520 of human JMJD2C.
Host
Rabbit
Reactivity
Human, Rat
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:10000)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of JMJD2C protein with JMJD2C polyclonal antibody (Cat # PAB8966).Enzyme-linked Immunoabsorbent Assay
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Gene Info — JMJD2C
Entrez GeneID
23081Gene Name
JMJD2C
Gene Alias
FLJ25949, GASC1, JHDM3C, KDM4C, KIAA0780, bA146B14.1
Gene Description
jumonji domain containing 2C
Omim ID
605469Gene Ontology
HyperlinkGene Summary
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
JmjC domain-containing histone demethylation protein 3C|OTTHUMP00000021052|OTTHUMP00000044461|gene amplified in squamous cell carcinoma 1
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Interactome
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Disease
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