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Last updated: 2017/4/23
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HDC polyclonal antibody

  • Catalog # : PAB8756
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of HDC.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 22 of human HDC.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 73
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody detects the 73 KDa full length HDC. It does not cross react with DOPA decarboxylase (DDC).
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of HDC expression in rat fetal liver tissue lysate. The antibody detects the 73 KDa full length HDC in samples from human, mouse and rat origins.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3067
  • Gene Name:
  • HDC
  • Gene Alias:
  • MGC163399
  • Gene Description:
  • histidine decarboxylase
  • Gene Summary:
  • The biogenic amine histamine is an important modulator of numerous physiologic processes, including neurotransmission, gastric acid secretion, and smooth muscle tone. The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase (HDC; EC 4.1.1.22). This homodimeric enzyme is a pyridoxal phosphate (PLP)-dependent decarboxylase and is highly specific for its histidine substrate.[supplied by OMIM
  • Other Designations:
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