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Last updated: 2017/3/26
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HDAC5 polyclonal antibody

  • Catalog # : PAB8752
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of HDAC5.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 575 of human HDAC5.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 124
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody detects ~124 KDa histone deacetylase 5. It does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 6, 7, and 8.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    Immunoprecipitation (20 ug/mL)
    Immunohistochemistry (20 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HDAC5 expression in Jurkat cell lysate. The antibody detects ~124 kDa HDAC5.
  • Immunohistochemistry
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • Gene Information
  • Gene Name:
  • HDAC5
  • Gene Alias:
  • FLJ90614,HD5,NY-CO-9
  • Gene Description:
  • histone deacetylase 5
  • Gene Summary:
  • Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • antigen NY-CO-9
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