Rabbit polyclonal antibody raised against synthetic peptide of SELE.
A synthetic peptide corresponding to residues surrounding amino acids 584 of human SELE.
Theoretical MW (kDa):
Human, Mouse, Rat
This antibody recognizes 67 KDa E-Selectin.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Western Blot (0.5-4 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10-20 ug/mL) Immunoprecipitation (10-20 ug/mL) The optimal working dilution should be determined by the end user.
In PBS (0.02% thimerosal)
Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq