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Last updated: 2017/5/21
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CLEC7A polyclonal antibody

  • Catalog # : PAB8670
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CLEC7A.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 161 of human CLEC7A.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 28
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody recognizes 28 KDa of Dectin-1 from samples of human origins. A ~16 KDa monomeric form and a 43 KDa glycoprotein can also be detected.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of CLEC7A expression in lysate from rat kidney (Lane 1) , NIH/3T3 cells (Lane 2) and Jurkat cells (Lane 3 & 4) .
  • Application Image
  • Gene Information
  • Gene Name:
  • CLEC7A
  • Gene Alias:
  • BGR,CLECSF12,DECTIN1
  • Gene Description:
  • C-type lectin domain family 7, member A
  • Gene Summary:
  • This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq
  • Other Designations:
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12,beta-glucan receptor,dectin-1,dendritic cell-associated C-type lectin 1,dendritic cell-associated C-type lectin-1,lectin-like receptor 1
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