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Last updated: 2017/8/13
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CYP2E1 polyclonal antibody

  • Catalog # : PAB8667
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CYP2E1.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 405 of human CYP2E1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 58
  • Reactivity:
  • Dog, Human, Mouse, Rat
  • Specificity:
  • This antibody detects ~58KDa cytochrome P450 IIE1.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of CYP2E1 polyclonal antibody (Cat # PAB8667) using rat kidney tissue lysate.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1571
  • Gene Name:
  • CYP2E1
  • Gene Alias:
  • CPE1,CYP2E,P450-J,P450C2E
  • Gene Description:
  • cytochrome P450, family 2, subfamily E, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020813,OTTHUMP00000046571,cytochrome P450 2E1,cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1,flavoprotein-linked monooxygenase,microsomal monooxygenase,xenobiotic monooxygenase
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