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TRAF3IP2 polyclonal antibody

  • Catalog # : PAB8654
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TRAF3IP2.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human TRAF3IP2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 63
  • Reactivity:
  • Human
  • Specificity:
  • This antibody detects the ~63 KDa human CIKS/Act1.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of TRAF3IP2 expression in human lung tissue lysate.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • TRAF3IP2
  • Gene Alias:
  • ACT1,C6orf2,C6orf4,C6orf5,C6orf6,CIKS,DKFZp586G0522,MGC3581
  • Gene Description:
  • TRAF3 interacting protein 2
  • Gene Summary:
  • This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq
  • Other Designations:
  • NFkB-activating protein ACT1,OTTHUMP00000017022,OTTHUMP00000017024,OTTHUMP00000040422,connection to IKK and SAPK/JNK
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