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Last updated: 2017/1/15
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CCR1 polyclonal antibody

  • Catalog # : PAB8640
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CCR1.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 341 of human CCR1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 42
  • Reactivity:
  • Human, Monkey, Mouse
  • Specificity:
  • The anti-CCR1 antibody recognizes 42 KDa human and monkey CCR1 and in a lesser extent the mouse CCR1 in Western blot analysis.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of CCR1 expression in Jurkat cell lysate.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1230
  • Gene Name:
  • CCR1
  • Gene Alias:
  • CD191,CKR-1,CKR1,CMKBR1,HM145,MIP1aR,SCYAR1
  • Gene Description:
  • chemokine (C-C motif) receptor 1
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq
  • Other Designations:
  • RANTES receptor
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