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Last updated: 2017/11/19
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CTSK polyclonal antibody

  • Catalog # : PAB8635
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CTSK.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 321 of human CTSK.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 43, 29
  • Reactivity:
  • Chicken, Human, Mouse, Pig, Rabbit, Rat
  • Specificity:
  • This antibody detects proform (43 KDa) and the mature form (29 KDa) of cathepsin K.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of CTSK expression in rat kidney tissue lysate.
  • Immunohistochemistry
  • Immunoprecipitation
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 1513
  • Gene Name:
  • CTSK
  • Gene Alias:
  • CTS02,CTSO,CTSO1,CTSO2,MGC23107,PKND,PYCD
  • Gene Description:
  • cathepsin K
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032938,cathepsin O1,cathepsin O2,cathepsin X
  • Gene Pathway
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