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Last updated: 2016/10/23
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ANXA7 polyclonal antibody

  • Catalog # : PAB8538
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ANXA7.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 316 of human ANXA7.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 36
  • Reactivity:
  • Human
  • Specificity:
  • This antibody detects 36 KDa ANXA7 of human origin. The ~28-30 KDa cleavage fragments can also be detected in Jurkat cell lysate.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of ANXA7 expression in Jurkat cell lysate.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 310
  • Gene Name:
  • ANXA7
  • Gene Alias:
  • Gene Description:
  • annexin A7
  • Gene Summary:
  • Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019812,OTTHUMP00000019813,OTTHUMP00000042922,OTTHUMP00000042923,OTTHUMP00000042925,annexin VII
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