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Last updated: 2016/12/4
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AAK1 polyclonal antibody

  • Catalog # : PAB8529
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of AAK1.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 850 of human AAK1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 95
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody recognizes ~95 KDa AAK1 in samples from human, mouse and rat origins.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of AAK1 expression in NIH/3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 2) .
  • Application Image
  • Gene Information
  • Gene Name:
  • AAK1
  • Gene Alias:
  • DKFZp686F03202,DKFZp686K16132,FLJ23712,FLJ25931,FLJ31060,FLJ42882,FLJ45252,KIAA1048,MGC138170,MGC164568,MGC164570
  • Gene Description:
  • AP2 associated kinase 1
  • Gene Summary:
  • Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • adaptor-associated kinase 1
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