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Last updated: 2017/1/22
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BCL2A1 polyclonal antibody

  • Catalog # : PAB8528
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of BCL2A1.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 37 of human BCL2A1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody detects A1 (Bfl-1) of human, mouse, and rat origins.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of BCL2A1 expression in Jurkat cell lysate (Lane 1) , mouse small intestine tissue lysate (Lane 2) and rat kidney tissue lysate (Lane 3) .
  • Immunohistochemistry
  • Immunoprecipitation
  • Application Image
  • Immunohistochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 597
  • Gene Name:
  • BCL2A1
  • Gene Alias:
  • ACC-1,ACC-2,BCL2L5,BFL1,GRS,HBPA1
  • Gene Description:
  • BCL2-related protein A1
  • Gene Summary:
  • This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • hematopoietic BCL2-related protein A1
  • Gene Pathway
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