S14G-Humanin polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of S14G-Humanin.
Immunogen
A synthetic peptide corresponding to human S14G-Humanin.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western blot analysis of extract from humanin peptide (lane 1) and S14G-humanin peptide (lane 2) , using S14G-Humanin polyclonal antibody (Cat # PAB8508) . -
Publication Reference
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Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization.
Terashita K, Hashimoto Y, Niikura T, Tajima H, Yamagishi Y, Ishizaka M, Kawasumi M, Chiba T, Kanekura K, Yamada M, Nawa M, Kita Y, Aiso S, Nishimoto I.
Journal of Neurochemistry 2003 Jun; 85(6):1521.
Application:WB, Mouse, Mouse primary neurons.
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Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults.
Tajima H, Niikura T, Hashimoto Y, Ito Y, Kita Y, Terashita K, Yamazaki K, Koto A, Aiso S, Nishimoto I.
Neuroscience Letters 2002 May; 324(3):227.
Application:IHC, WB, Human, Mouse, Brains, Colons, Testis.
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Detailed characterization of neuroprotection by a rescue factor humanin against various Alzheimer's disease-relevant insults.
Hashimoto Y, Niikura T, Ito Y, Sudo H, Hata M, Arakawa E, Abe Y, Kita Y, Nishimoto I.
Journal of Neuroscience 2001 Dec; 21(23):9235.
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A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.
Hashimoto Y, Niikura T, Tajima H, Yasukawa T, Sudo H, Ito Y, Kita Y, Kawasumi M, Kouyama K, Doyu M, Sobue G, Koide T, Tsuji S, Lang J, Kurokawa K, Nishimoto I.
PNAS 2001 May; 98(11):6336.
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Mechanisms of neuroprotection by a novel rescue factor humanin from Swedish mutant amyloid precursor protein.
Hashimoto Y, Ito Y, Niikura T, Shao Z, Hata M, Oyama F, Nishimoto I.
Biochemical and Biophysical Research Communications 2001 May; 283(2):460.
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Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization.
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