Trpv4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Trpv4.
Immunogen
A synthetic peptide corresponding to mouse Trpv4.
Host
Rabbit
Reactivity
Mouse
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (3-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western blot analysis of extract from Lane 1: choroid plexus (Wild type mouse) , Lane 2: choroid plexus (Trpv4 knockout mouse) and Lane 3: rat Trpv4 overexpressed in HEK 293T cells, using Trpv4 polyclonal antibody (Cat # PAB8503) . -
Gene Info — Trpv4
Entrez GeneID
63873Gene Name
Trpv4
Gene Alias
0610033B08Rik, MGC150050, OTRPC4, Trp12, VR-OAC, VRL-2, VROAC
Gene Description
transient receptor potential cation channel, subfamily V, member 4
Gene Ontology
HyperlinkGene Summary
subfamily V
Other Designations
OTTMUSP00000015421|OTTMUSP00000015422|osmosensitive transient receptor potential channel 4|transient receptor potential protein 12
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Publication Reference
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Effects of body temperature on neural activity in the hippocampus: regulation of resting membrane potentials by transient receptor potential vanilloid 4.
Shibasaki K, Suzuki M, Mizuno A, Tominaga M.
Journal of Neuroscience 2007 Feb; 27(7):1566.
Application:WB, Mouse, Mouse hippocampal neurons.
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Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat.
Alessandri-Haber N, Dina OA, Yeh JJ, Parada CA, Reichling DB, Levine JD.
Journal of Neuroscience 2004 May; 24(18):4444.
Application:Flow Cyt, IHC, WB, Rat, Saphenous nerve.
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Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.
Watanabe H, Vriens J, Prenen J, Droogmans G, Voets T, Nilius B.
Nature 2003 Jul; 424(6947):434.
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Impaired osmotic sensation in mice lacking TRPV4.
Mizuno A, Matsumoto N, Imai M, Suzuki M.
American Journal of Physiology. Cell Physiology 2003 Jul; 285(1):C96.
Application:IHC, WB, Mouse, Mouse kidneys.
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Warm temperatures activate TRPV4 in mouse 308 keratinocytes.
Chung MK, Lee H, Caterina MJ.
The Journal of Biological Chemistry 2003 Aug; 278(34):32037.
Application:IF, WB-Tr, Human, Mouse, 308, HEK 293 cells.
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Effects of body temperature on neural activity in the hippocampus: regulation of resting membrane potentials by transient receptor potential vanilloid 4.
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