ADIPOR1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ADIPOR1.
Immunogen
A synthetic peptide corresponding to human ADIPOR1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot analysis of extract from mouse muscle tissue (lane 1) and mouse heart tissue (lane 2) , using ADIPOR1 polyclonal antibody (Cat # PAB8501) . -
Gene Info — ADIPOR1
Entrez GeneID
51094Gene Name
ADIPOR1
Gene Alias
ACDCR1, CGI-45, CGI45, FLJ25385, FLJ42464, PAQR1, TESBP1A
Gene Description
adiponectin receptor 1
Omim ID
607945Gene Ontology
HyperlinkGene Summary
The adiponectin receptors, ADIPOR1 and ADIPOR2 (MIM 607946), serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM
Other Designations
OTTHUMP00000038805
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Interactome
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Pathway
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Disease
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Publication Reference
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Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity.
Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Hara K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T.
The Journal of Biological Chemistry 2004 Jul; 279(29):30817.
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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.
Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T.
Nature 2003 Jun; 423(6941):762.
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Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity.
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