TENC1 polyclonal antibody
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More Files
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Immunohistochemistry
Imunohistochemical analysis of mouse kidney tissue, using TENC1 polyclonal antibody (Cat # PAB8498) .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TENC1.
Immunogen
A synthetic peptide corresponding to N-terminus of human TENC1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunohistochemistry (5 ug/mL)
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Imunohistochemical analysis of mouse kidney tissue, using TENC1 polyclonal antibody (Cat # PAB8498) . -
Gene Info — TENC1
Entrez GeneID
23371Gene Name
TENC1
Gene Alias
C1-TEN, C1TEN, DKFZp686D13244, FLJ16320, KIAA1075, TNS2
Gene Description
tensin like C1 domain containing phosphatase (tensin 2)
Omim ID
607717Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq
Other Designations
tensin 2|tensin like C1 domain containing phosphatase|tensin like C1 domain-containing phosphatase
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Interactome
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Publication Reference
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Tensin.
Lo SH.
The International Journal of Biochemistry & Cell Biology 2004 Jan; 36(1):31.
Application：IHC, WB, Human, Human tissues.
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Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.
Calderwood DA, Fujioka Y, de Pereda JM, García-Alvarez B, Nakamoto T, Margolis B, McGlade CJ, Liddington RC, Ginsberg MH.
PNAS 2003 Mar; 100(5):2272.
Application：WB, Recombinant protein.
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Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer.
Lo SH, Lo TB.
Cancer Research 2002 Aug; 62(15):4217.
Application：IF, WB-Ce, Human, MLC, LnCap, DU145, PC3 cells.
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Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migration.
Chen H, Duncan IC, Bozorgchami H, Lo SH.
PNAS 2002 Jan; 99(2):733.
Application：WB-Tr, Human, Mouse, HEK 293, NIH/3T3 cells.
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Progressive kidney degeneration in mice lacking tensin.
Lo SH, Yu QC, Degenstein L, Chen LB, Fuchs E.
The Journal of Cell Biology 1997 Mar; 136(6):1349.
Application：IEM, IHC-P, Mouse, Mouse kidneys.
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Tensin.
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