CAPN6 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extract from NIH/3T3 cells, using CAPN6 polyclonal antibody (Cat # PAB8485) .
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CAPN6.
Immunogen
A synthetic peptide corresponding to human CAPN6.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (2-5 ug/mL)
Immunohistochemistry (20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of extract from NIH/3T3 cells, using CAPN6 polyclonal antibody (Cat # PAB8485) .Immunohistochemistry
-
Gene Info — CAPN6
Entrez GeneID
827Gene Name
CAPN6
Gene Alias
CANPX, CAPNX, CalpM, DJ914P14.1
Gene Description
calpain 6
Omim ID
300146Gene Ontology
HyperlinkGene Summary
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. It also lacks critical active site residues and thus is suggested to be proteolytically inactive. [provided by RefSeq
Other Designations
OTTHUMP00000023858|calpain-like protease|calpamodulin
-
Interactome
-
Disease
-
Publication Reference
-
The calpain family and human disease.
Huang Y, Wang KK.
Trends in Molecular Medicine 2001 Aug; 7(8):355.
Application：IHC, WB, Human, Mouse, Rat, Placenta.
-
Genomic organization of mouse Capn5 and Capn6 genes confirms that they are a distinct calpain subfamily.
Matena K, Boehm T, Dear N.
Genomics 1998 Feb; 48(1):117.
-
A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution.
Dear N, Matena K, Vingron M, Boehm T.
Genomics 1997 Oct; 45(1):175.
-
The calpain family and human disease.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com