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TREM1 polyclonal antibody

  • Catalog # : PAB8442
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  • Specification
  • Product Description:
  • Sheep polyclonal antibody raised against partial length recombinant TREM1.
  • Immunogen:
  • Recombinant His fusion protein corresponding to amino acids 21-200 of human TREM1.
  • Host:
  • Sheep
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM phosphate buffer, 150 mM NaCl, pH 7.2 (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Gene Name:
  • TREM1
  • Gene Alias:
  • TREM-1
  • Gene Description:
  • triggering receptor expressed on myeloid cells 1
  • Gene Summary:
  • Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000016370,triggering-receptor TREM1
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