IL12A polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against partial length recombinant IL12A.
Immunogen
Recombinant His fusion protein corresponding to amino acids 57-253 of human IL12A.
Host
Sheep
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 20 mM phosphate buffer, 150 mM NaCl, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL12A
Entrez GeneID
3592Gene Name
IL12A
Gene Alias
CLMF, IL-12A, NFSK, NKSF1, P35
Gene Description
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
Omim ID
161560Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq
Other Designations
IL-12, subunit p35|NF cell stimulatory factor chain 1|cytotoxic lymphocyte maturation factor 1, p35|interleukin 12, p35|interleukin 12A|interleukin-12 alpha chain|natural killer cell stimulatory factor 1, 35 kD subunit
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Interactome
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Disease
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