STMN1 (phospho S25) polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of STMN1.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding S25 of human STMN1.
Host
Rabbit
Theoretical MW (kDa)
19
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Immunoaffinity purification
Concentration
1 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Phospho-STMN1 Ser24 polyclonal antibody. Western blot analysis of STMN1 expression in rat brain.Western Blot (Cell lysate)
Phospho-STMN1 Ser24 polyclonal antibody. Western blot analysis of STMN1 expression in Hela.Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STMN1 (phospho S25) polyclonal antibody (Cat # PAB8195). -
Gene Info — STMN1
Entrez GeneID
3925Gene Name
STMN1
Gene Alias
LAP18, Lag, OP18, PP17, PP19, PR22, SMN
Gene Description
stathmin 1/oncoprotein 18
Omim ID
151442Gene Ontology
HyperlinkGene Summary
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000008527|OTTHUMP00000008528|OTTHUMP00000008530|leukemia-associated phosphoprotein p18|metablastin|oncoprotein 18|phosphoprotein 19|prosolin|stathmin 1
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Publication Reference
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Comparative phosphoproteomic analysis of checkpoint recovery identifies new regulators of the DNA damage response.
Halim VA, Alvarez-Fernandez M, Xu YJ, Aprelia M, van den Toorn HW, Heck AJ, Mohammed S, Medema RH.
Science Signaling 2013 Apr; 6(272):rs9.
Application:WB-Ce, Human, U-2 OS cells.
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Comparative phosphoproteomic analysis of checkpoint recovery identifies new regulators of the DNA damage response.
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