TIMP3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TIMP3.
Immunogen
A synthetic peptide corresponding to amino acids 198-211 at C-terminus of human TIMP3.
Sequence
WAPPDKSIINATDP
Host
Rabbit
Theoretical MW (kDa)
24.1
Reactivity
Human, Mouse, Rat
Form
Lyophilized
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (0.1-0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of rat kidney tissue lysate. Using TIMP3 polyclonal antibody (Cat # PAB8014) . -
Gene Info — TIMP3
Entrez GeneID
7078Gene Name
TIMP3
Gene Alias
HSMRK222, K222, K222TA2, SFD
Gene Description
TIMP metallopeptidase inhibitor 3
Gene Ontology
HyperlinkGene Summary
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq
Other Designations
MIG-5 protein|tissue inhibitor of metalloproteinase 3
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Interactome
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Disease
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Publication Reference
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Genomic organization of the human tissue inhibitor of metalloproteinases-3 (TIMP3).
Stohr H, Roomp K, Felbor U, Weber BH.
Genome Research 1995 Dec; 5(5):483.
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Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22.
Apte SS, Mattei MG, Olsen BR.
Genomics 1994 Jan; 19(1):86.
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Genomic organization of the human tissue inhibitor of metalloproteinases-3 (TIMP3).
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