Rabbit polyclonal antibody raised against synthetic peptide of BNIP3.
A synthetic peptide corresponding to amino acids at C-terminus of human BNIP3.
Theoretical MW (kDa):
Human, Mouse, Rabbit, Rat
Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Immunohistochemistry (Frozen sections) (0.5-1 ug/mL) Immunocytochemistry (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. This gene contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. [provided by RefSeq
BCL2/adenovirus E1B 19kD-interacting protein 3,OTTHUMP00000020752