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Last updated: 2016/10/23
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CXCR2 polyclonal antibody

  • Catalog # : PAB7969
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CXCR2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human CXCR2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 40.7
  • Reactivity:
  • Human, Rat
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of human colon cancer lysate. Using CXCR2 polyclonal antibody (Cat # PAB7969) .
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3579
  • Gene Name:
  • CXCR2
  • Gene Alias:
  • CD182,CDw128b,CMKAR2,IL8R2,IL8RA,IL8RB
  • Gene Description:
  • chemokine (C-X-C motif) receptor 2
  • Gene Summary:
  • The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq
  • Other Designations:
  • C-X-C chemokine receptor type 2,CXC-R2,CXCR-2,CXCR2 gene for IL8 receptor type B,GRO/MGSA receptor,IL-8 receptor type 2,IL-8R B,chemokine (CXC) receptor 2,high affinity interleukin-8 receptor B,interleukin 8 receptor B,interleukin 8 receptor type 2,interl
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