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Last updated: 2016/11/27
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JUP (phospho Y550) polyclonal antibody

  • Catalog # : PAB7924
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of JUP.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y550 of human JUP.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This peptide sequence is highly conserved in rat and mouse g-Catenin.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:2000)
    Western Blot (1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of JUP immunoprecipitated from lysates prepared from A-431 cells treated with pervanadate. The immunoprecipitation was performed using mouse JUP monoclonal antibody. The blots were probed with either JUP (phospho Y550) polyclonal antibody (Cat # PAB7924). The immunoprecipitated JUP was untreated (lane 1) or treated with alkaline phosphatase (lane 2) then probed with the antibodies. In addition, the JUP (phospho Y550) polyclonal antibody (Cat # PAB7924) was used in the presence of phospho-JUP (Tyr-550) peptide (lane 3) or phospho-JUP (Tyr-644) peptide (lane 4).
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3728
  • Gene Name:
  • JUP
  • Gene Alias:
  • ARVD12,CTNNG,DP3,DPIII,PDGB,PKGB
  • Gene Description:
  • junction plakoglobin
  • Gene Summary:
  • This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000164735,catenin (cadherin-associated protein), gamma (80kD),catenin (cadherin-associated protein), gamma 80kDa,gamma-catenin
  • Interactome
  • Interactome
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