Immunocytochemical labeling in chick dorsal root ganglion neurons using CFL1 polyclonal antibody (Cat # PAB7882) . (Images provided by Dr. Diane Snow, Department of Anatomy & Neurobiology, University of Kentucky).
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM