HEK293 lysate (10 ug protein in RIPA buffer) over expressing human UCN3 with DYKDDDDK tag probed with UCN3 polyclonal antibody (Cat # PAB7613) (1 ug/mL) in Lane 1 and probed with anti- DYKDDDDK Tag (1/3000) in lane 3. Mock-transfected HEK293 probed with UCN3 polyclonal antibody (Cat # PAB7613) (1 mg/mL) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq
OTTHUMP00000018999,stresscopin,urocortin 3,urocortin III