TUSC3 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
TUSC3 polyclonal antibody (Cat # PAB7612) (1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TUSC3.
Immunogen
A synthetic peptide corresponding to human TUSC3.
Sequence
PQRQCSVCRQAN
Host
Goat
Theoretical MW (kDa)
39.7, 39.6
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_006756.2; NP_839952.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TUSC3 polyclonal antibody (Cat # PAB7612) (1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TUSC3
Entrez GeneID
7991Protein Accession#
NP_006756.2;NP_839952.1Gene Name
TUSC3
Gene Alias
D8S1992, M33, MGC13453, MRT7, N33, OST3A
Gene Description
tumor suppressor candidate 3
Gene Ontology
HyperlinkGene Summary
This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000120036|Putative prostate cancer tumor suppressor
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Interactome
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Publication Reference
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Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival.
Pils D, Horak P, Gleiss A, Sax C, Fabjani G, Moebus VJ, Zielinski C, Reinthaller A, Zeillinger R, Krainer M.
Cancer 2005 Dec; 104(11):2417.
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Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival.
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