TACR2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TACR2.
Immunogen
A synthetic peptide corresponding to human TACR2.
Sequence
STRVNRCHTKET
Host
Goat
Theoretical MW (kDa)
44.4
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TACR2
Entrez GeneID
6865Protein Accession#
NP_001048.2Gene Name
TACR2
Gene Alias
NK2R, NKNAR, SKR, TAC2R
Gene Description
tachykinin receptor 2
Omim ID
162321Gene Ontology
HyperlinkGene Summary
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq
Other Designations
NK-2 receptor|OTTHUMP00000019722|neurokinin 2 receptor|neurokinin A receptor|seven transmembrane helix receptor|substance K receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD.
Miotto D, Boschetto P, Cavallesco G, Zeni E, Querzoli P, Pedriali M, Chiarelli S, Fabbri LM, Mapp CE.
Histopathology 2007 Jul; 51(1):128.
Application：IHC-P, Human, Human peripheral lung.
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Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD.
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