RARRES3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of RARRES3.
Immunogen
A synthetic peptide corresponding to amino acids 124-136 of human RARRES3.
Sequence
KSRCKQVEKAKVE
Host
Goat
Theoretical MW (kDa)
18.8
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — RARRES3
Entrez GeneID
5920Protein Accession#
NP_004576.2Gene Name
RARRES3
Gene Alias
HRASLS4, MGC8906, RIG1, TIG3
Gene Description
retinoic acid receptor responder (tazarotene induced) 3
Omim ID
605092Gene Ontology
HyperlinkGene Summary
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq
Other Designations
retinoic acid-inducible gene 1
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Interactome
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Disease
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Publication Reference
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RIG1 suppresses Ras activation and induces cellular apoptosis at the Golgi apparatus.
Tsai FM, Shyu RY, Jiang SY.
Cellular Signalling 2007 May; 19(5):989.
Application：WB-Tr, Human, HtTA cells.
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RIG1 suppresses Ras activation and induces cellular apoptosis at the Golgi apparatus.
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