RASSF6 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of RASSF6.
Immunogen
A synthetic peptide corresponding to human RASSF6.
Sequence
C-SNTLKPHAKDEPDS
Host
Goat
Theoretical MW (kDa)
39.8, 43.4
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_803876.1; NP_958834.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
RASSF6 polyclonal antibody (Cat # PAB7596) (1 ug/mL) staining of HepG2 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RASSF6
Entrez GeneID
166824Protein Accession#
NP_803876.1;NP_958834.1Gene Name
RASSF6
Gene Alias
DKFZp686K23225
Gene Description
Ras association (RalGDS/AF-6) domain family member 6
Gene Ontology
HyperlinkGene Summary
RASSF6 is a member of the RAS association (RA) domain family of RAS effectors/tumor suppressors that mediate some of the growth inhibitory properties of RAS (see HRAS; MIM 190020) oncogenes (Eckfeld et al., 2004 [PubMed 15574778]).[supplied by OMIM
Other Designations
Ras association (RalGDS/AF-6) domain family 6|putative RAS binding protein
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Disease
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Publication Reference
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RASSF6 is a novel member of the RASSF family of tumor suppressors.
Allen NP, Donninger H, Vos MD, Eckfeld K, Hesson L, Gordon L, Birrer MJ, Latif F, Clark GJ.
Oncogene 2007 Sep; 26(42):6203.
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RASSF6 is a novel member of the RASSF family of tumor suppressors.
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