APOBEC3A polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of APOBEC3A.
Immunogen
A synthetic peptide corresponding to internal region of human APOBEC3A.
Sequence
C-TSNFNNGIGRHKTY
Host
Goat
Theoretical MW (kDa)
23
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:8000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
APOBEC3A polyclonal antibody (Cat # PAB7588) (3.8 ug/mL) staining of paraffin embedded human tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — APOBEC3A
Entrez GeneID
200315Protein Accession#
NP_663745.1Gene Name
APOBEC3A
Gene Alias
ARP3, PHRBN, bK150C2.1
Gene Description
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
Omim ID
607109Gene Ontology
HyperlinkGene Summary
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. This gene encodes a protein that lacks the zinc binding activity and may be an expressed pseudogene. [provided by RefSeq
Other Designations
phorbolin 1
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Interactome
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Pathway
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Publication Reference
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Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity.
Goila-Gaur R, Khan MA, Miyagi E, Kao S, Strebel K.
Retrovirology 2007 Aug; 4:61.
Application:IF, WB-Tr, Human, HeLa cells.
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Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity.
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