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Last updated: 2016/12/4
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IGFBP3 polyclonal antibody

  • Catalog # : PAB7567
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of IGFBP3.
  • Immunogen:
  • A synthetic peptide corresponding to human IGFBP3.
  • Sequence:
  • C-RYKVDYESQSTDTQN
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 31.7, 32.2
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_001013416.1 and NP_000589.2).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (0.02-0.06 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • IGFBP3 polyclonal antibody (Cat # PAB7567) (0.02 ug/mL) staining of human breast cancer lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3486
  • Protein Accession#:
  • NP_001013416.1;NP_000589.2
  • Gene Name:
  • IGFBP3
  • Gene Alias:
  • BP-53,IBP3
  • Gene Description:
  • insulin-like growth factor binding protein 3
  • Gene Summary:
  • This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • IGF-binding protein 3,acid stable subunit of the 140 K IGF complex,binding protein 29,binding protein 53,growth hormone-dependent binding protein
  • Gene Pathway
  • Related Disease
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