IGF2BP2 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
IGF2BP2 polyclonal antibody (Cat # PAB7566) (1 ug/mL) staining of HepG2 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot (Transfected lysate)
293 overexpressing IGF2BP2 and probed with IGF2BP2 polyclonal antibody (Cat # PAB7566) (mock transfection in first lane), tested by Origene.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of IGF2BP2.
Immunogen
A synthetic peptide corresponding to human IGF2BP2.
Sequence
C-KQQEQKYPQGVASQR
Host
Goat
Theoretical MW (kDa)
66.1, 61.8
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_006539.3 and NP_001007226.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
IGF2BP2 polyclonal antibody (Cat # PAB7566) (1 ug/mL) staining of HepG2 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Western Blot (Transfected lysate)
293 overexpressing IGF2BP2 and probed with IGF2BP2 polyclonal antibody (Cat # PAB7566) (mock transfection in first lane), tested by Origene.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — IGF2BP2
Entrez GeneID
10644Protein Accession#
NP_006539.3;NP_001007226.1Gene Name
IGF2BP2
Gene Alias
IMP-2, IMP2, VICKZ2, p62
Gene Description
insulin-like growth factor 2 mRNA binding protein 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
IGF II mRNA binding protein 2|IGF-II mRNA-binding protein 2|insulin-like 2 growth factor 2-binding protein 2
-
Interactome
-
Disease
-
Publication Reference
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JR, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney AS, McCarthy MI, Hattersley AT.
Science 2007 Jun; 316(5829):1336.
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com