GRIN2D polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GRIN2D.
Immunogen
A synthetic peptide corresponding to human GRIN2D.
Sequence
C-TRRGSAHFSSLESE
Host
Goat
Theoretical MW (kDa)
144
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — GRIN2D
Entrez GeneID
2906Protein Accession#
NP_000827.2Gene Name
GRIN2D
Gene Alias
EB11, NMDAR2D
Gene Description
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
Omim ID
602717Gene Ontology
HyperlinkGene Summary
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
Other Designations
N-methyl-D-aspartate receptor subunit 2D|estrogen receptor binding CpG island
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Interactome
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Pathway
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Disease
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Publication Reference
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NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock.
Clarke RJ, Johnson JW.
Journal of Neuroscience 2006 May; 26(21):5825.
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NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock.
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