GADD45G polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GADD45G.
Immunogen
A synthetic peptide corresponding to amino acids 123-133 of human GADD45G.
Sequence
C-SNPNEDAWKDP
Host
Goat
Theoretical MW (kDa)
17.1
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — GADD45G
Entrez GeneID
10912Protein Accession#
NP_006696.1Gene Name
GADD45G
Gene Alias
CR6, DDIT2, GADD45gamma, GRP17
Gene Description
growth arrest and DNA-damage-inducible, gamma
Omim ID
604949Gene Ontology
HyperlinkGene Summary
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq
Other Designations
GADD45-gamma|OTTHUMP00000021623|gadd-related protein, 17 kD
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Interactome
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Pathway
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Disease
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Publication Reference
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NF-kappa B-mediated repression of growth arrest- and DNA-damage-inducible proteins 45alpha and gamma is essential for cancer cell survival.
Zerbini LF, Wang Y, Czibere A, Correa RG, Cho JY, Ijiri K, Wei W, Joseph M, Gu X, Grall F, Goldring MB, Zhou JR, Libermann TA.
PNAS 2004 Sep; 101(37):13618.
Application：WB, Human, LNCaP cells.
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NF-kappa B-mediated repression of growth arrest- and DNA-damage-inducible proteins 45alpha and gamma is essential for cancer cell survival.
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