FGF21 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FGF21.
Immunogen
A synthetic peptide corresponding to human FGF21.
Sequence
CQRPDGALYGSLH
Host
Goat
Theoretical MW (kDa)
22.3
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
FGF21 polyclonal antibody (Cat # PAB7549) (1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FGF21
Entrez GeneID
26291Protein Accession#
NP_061986.1Gene Name
FGF21
Gene Alias
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Gene Description
fibroblast growth factor 21
Omim ID
609436Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Publication Reference
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Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21.
Inagaki T, Dutchak P, Zhao G, Ding X, Gautron L, Parameswara V, Li Y, Goetz R, Mohammadi M, Esser V, Elmquist JK, Gerard RD, Burgess SC, Hammer RE, Mangelsdorf DJ, Kliewer SA.
Cell Metabolism 2007 Jun; 5(6):415.
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Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21.
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