ENOX2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ENOX2.
Immunogen
A synthetic peptide corresponding to human ENOX2.
Sequence
C-EKLKDDKLQVEK
Host
Goat
Theoretical MW (kDa)
66.6, 70.1
Specificity
This antibody is expected to recognize both reported isoforms (NP_006366.2; NP_872114.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ENOX2
Entrez GeneID
10495Protein Accession#
NP_006366.2;NP_872114.1Gene Name
ENOX2
Gene Alias
APK1, COVA1, tNOX
Gene Description
ecto-NOX disulfide-thiol exchanger 2
Omim ID
300282Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a growth-related cell surface protein. It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The two activities alternate with a period length of about 24 minutes. The encoded protein also displays prion-like properties. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
APK1 antigen|OTTHUMP00000024021|OTTHUMP00000024022|cytosolic ovarian carcinoma antigen 1
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Interactome
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Publication Reference
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tNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin-3-gallate.
Chueh PJ, Wu LY, Morre DM, Morre DJ.
BioFactors (Oxford, England) 2004 Jan; 20(4):235.
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tNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin-3-gallate.
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